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Growth Hormone Protects Against Ovariectomy-Induced Bone Loss in States of Low Circulating Insulin-like Growth Factor (IGF-1)*
Early after estrogen loss in postmenopausal women and ovariectomy (OVX) of animals, accelerated endosteal bone resorption leads to marrow expansion of long bone shafts that reduce mechanical integrity. Both growth hormone (GH) and insulin-like growth factor (IGF-1) are potent regulators of bone remo...
Autores principales: | Fritton, J Christopher, Emerton, Kelly B, Sun, Hui, Kawashima, Yuki, Mejia, Wilson, Wu, Yingjie, Rosen, Clifford J, Panus, David, Bouxsein, Mary, Majeska, Robert J, Schaffler, Mitchell B, Yakar, Shoshana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153382/ https://www.ncbi.nlm.nih.gov/pubmed/19619004 http://dx.doi.org/10.1359/jbmr.090723 |
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