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Intrinsic resistance to tyrosine kinase inhibitors is associated with poor clinical outcome in metastatic renal cell carcinoma
BACKGROUND: Data on sequential therapy in patients with metastatic renal cell carcinoma (mRCC) and intrinsic resistance to receptor tyrosine kinase inhibitor (rTKI) treatment remains vague. METHODS: We retrospectively studied treatment characteristics and outcome of mRCC patients refractory to first...
Autores principales: | Busch, Jonas, Seidel, Christoph, Weikert, Steffen, Wolff, Ingmar, Kempkensteffen, Carsten, Weinkauf, Lisa, Hinz, Stefan, Magheli, Ahmed, Miller, Kurt, Grünwald, Viktor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154177/ https://www.ncbi.nlm.nih.gov/pubmed/21756335 http://dx.doi.org/10.1186/1471-2407-11-295 |
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