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Expression and Genetic Loss of Function Analysis of the HAT/DESC Cluster Proteases TMPRSS11A and HAT
Genome mining at the turn of the millennium uncovered a new family of type II transmembrane serine proteases (TTSPs) that comprises 17 members in humans and 19 in mice. TTSPs phylogenetically belong to one of four subfamilies: matriptase, hepsin/TMPRSS, corin and HAT/DESC. Whereas a wealth of inform...
Autores principales: | Sales, Katiuchia Uzzun, Hobson, John P., Wagenaar-Miller, Rebecca, Szabo, Roman, Rasmussen, Amber L., Bey, Alexandra, Shah, Maham F., Molinolo, Alfredo A., Bugge, Thomas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154331/ https://www.ncbi.nlm.nih.gov/pubmed/21853097 http://dx.doi.org/10.1371/journal.pone.0023261 |
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