Ascorbic acid in Charcot–Marie–Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trial

BACKGROUND: Ascorbic acid reduced the severity of neuropathy in transgenic mice overexpressing peripheral myelin protein 22 (PMP22), a model of Charcot–Marie–Tooth disease type 1A (CMT1A) associated with the PMP22 duplication. However, in three 1-year trials, ascorbic acid had no benefit in human be...

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Detalles Bibliográficos
Autores principales: Pareyson, Davide, Reilly, Mary M, Schenone, Angelo, Fabrizi, Gian Maria, Cavallaro, Tiziana, Santoro, Lucio, Vita, Giuseppe, Quattrone, Aldo, Padua, Luca, Gemignani, Franco, Visioli, Francesco, Laurà, Matilde, Radice, Davide, Calabrese, Daniela, Hughes, Richard AC, Solari, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Pub. Group 2011
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154498/
https://www.ncbi.nlm.nih.gov/pubmed/21393063
http://dx.doi.org/10.1016/S1474-4422(11)70025-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154498/
https://www.ncbi.nlm.nih.gov/pubmed/21393063
http://dx.doi.org/10.1016/S1474-4422(11)70025-4

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