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Let-7a Is a Direct EWS-FLI-1 Target Implicated in Ewing's Sarcoma Development

Ewing's sarcoma family tumors (ESFT) are the second most common bone malignancy in children and young adults, characterized by unique chromosomal translocations that in 85% of cases lead to expression of the EWS-FLI-1 fusion protein. EWS-FLI-1 functions as an aberrant transcription factor that...

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Detalles Bibliográficos
Autores principales:	De Vito, Claudio, Riggi, Nicolo, Suvà, Mario-Luca, Janiszewska, Michalina, Horlbeck, Janine, Baumer, Karine, Provero, Paolo, Stamenkovic, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154507/ https://www.ncbi.nlm.nih.gov/pubmed/21853155 http://dx.doi.org/10.1371/journal.pone.0023592

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