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Association of Human TLR1 and TLR6 Deficiency with Altered Immune Responses to BCG Vaccination in South African Infants

The development of effective immunoprophylaxis against tuberculosis (TB) remains a global priority, but is hampered by a partially protective Bacillus Calmette-Guérin (BCG) vaccine and an incomplete understanding of the mechanisms of immunity to Mycobacterium tuberculosis. Although host genetic fact...

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Detalles Bibliográficos
Autores principales: Randhawa, April Kaur, Shey, Muki S., Keyser, Alana, Peixoto, Blas, Wells, Richard D., de Kock, Marwou, Lerumo, Lesedi, Hughes, Jane, Hussey, Gregory, Hawkridge, Anthony, Kaplan, Gilla, Hanekom, Willem A., Hawn, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154845/
https://www.ncbi.nlm.nih.gov/pubmed/21852947
http://dx.doi.org/10.1371/journal.ppat.1002174