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Association of Human TLR1 and TLR6 Deficiency with Altered Immune Responses to BCG Vaccination in South African Infants
The development of effective immunoprophylaxis against tuberculosis (TB) remains a global priority, but is hampered by a partially protective Bacillus Calmette-Guérin (BCG) vaccine and an incomplete understanding of the mechanisms of immunity to Mycobacterium tuberculosis. Although host genetic fact...
Autores principales: | Randhawa, April Kaur, Shey, Muki S., Keyser, Alana, Peixoto, Blas, Wells, Richard D., de Kock, Marwou, Lerumo, Lesedi, Hughes, Jane, Hussey, Gregory, Hawkridge, Anthony, Kaplan, Gilla, Hanekom, Willem A., Hawn, Thomas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154845/ https://www.ncbi.nlm.nih.gov/pubmed/21852947 http://dx.doi.org/10.1371/journal.ppat.1002174 |
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