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Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans

In eukaryotic cells, the unfolded protein response (UPR) pathway plays a crucial role in cellular homeostasis of the endoplasmic reticulum (ER) during exposure to diverse environmental conditions that cause ER stress. Here we report that the human fungal pathogen Cryptococcus neoformans has evolved...

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Detalles Bibliográficos
Autores principales: Cheon, Seon Ah, Jung, Kwang-Woo, Chen, Ying-Lien, Heitman, Joseph, Bahn, Yong-Sun, Kang, Hyun Ah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154848/
https://www.ncbi.nlm.nih.gov/pubmed/21852949
http://dx.doi.org/10.1371/journal.ppat.1002177