Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum–associated degradation

The Hsp/c70 cytosolic chaperone system facilitates competing pathways of protein folding and degradation. Here we use a reconstituted cell-free system to investigate the mechanism and extent to which Hsc70 contributes to these co- and posttranslational decisions for the membrane protein cystic fibro...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsumura, Yoshihiro, David, Larry L., Skach, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154877/
https://www.ncbi.nlm.nih.gov/pubmed/21697503
http://dx.doi.org/10.1091/mbc.E11-02-0137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154877/
https://www.ncbi.nlm.nih.gov/pubmed/21697503
http://dx.doi.org/10.1091/mbc.E11-02-0137

Ejemplares similares