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Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum–associated degradation

The Hsp/c70 cytosolic chaperone system facilitates competing pathways of protein folding and degradation. Here we use a reconstituted cell-free system to investigate the mechanism and extent to which Hsc70 contributes to these co- and posttranslational decisions for the membrane protein cystic fibro...

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Detalles Bibliográficos
Autores principales:	Matsumura, Yoshihiro, David, Larry L., Skach, William R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154877/ https://www.ncbi.nlm.nih.gov/pubmed/21697503 http://dx.doi.org/10.1091/mbc.E11-02-0137

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