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The spindle checkpoint protein Mad2 regulates APC/C activity during prometaphase and metaphase of meiosis I in Saccharomyces cerevisiae

In many eukaryotes, disruption of the spindle checkpoint protein Mad2 results in an increase in meiosis I nondisjunction, suggesting that Mad2 has a conserved role in ensuring faithful chromosome segregation in meiosis. To characterize the meiotic function of Mad2, we analyzed individual budding yea...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Dai, Gonzalez, Claire, Lacefield, Soni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154881/
https://www.ncbi.nlm.nih.gov/pubmed/21697504
http://dx.doi.org/10.1091/mbc.E11-04-0378