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Yos9p assists in the degradation of certain nonglycosylated proteins from the endoplasmic reticulum

The HRD ubiquitin ligase recognizes and ubiquitylates proteins of the endoplasmic reticulum that display structural defects. Here, we apply quantitative proteomics to characterize the substrate spectrum of the HRD complex. Among the identified substrates is Erg3p, a glycoprotein involved in sterol s...

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Detalles Bibliográficos
Autores principales:	Jaenicke, Laura A., Brendebach, Holger, Selbach, Matthias, Hirsch, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154888/ https://www.ncbi.nlm.nih.gov/pubmed/21737688 http://dx.doi.org/10.1091/mbc.E10-10-0832

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