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A Comparison of Exogenous Promoter Activity at the ROSA26 Locus Using a PhiC31 Integrase Mediated Cassette Exchange Approach in Mouse ES Cells

The activities of nine ubiquitous promoters (ROSA26, CAG, CMV, CMVd1, UbC, EF1α, PGK, chicken β-actin and MC1) have been quantified and compared in mouse embryonic stem cells. To avoid the high variation in transgene expression which results from uncontrolled copy number and chromosomal position eff...

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Detalles Bibliográficos
Autores principales:	Chen, Chiann-mun, Krohn, Jon, Bhattacharya, Shoumo, Davies, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154917/ https://www.ncbi.nlm.nih.gov/pubmed/21853122 http://dx.doi.org/10.1371/journal.pone.0023376

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