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Drug-Resistant Genotypes and Multi-Clonality in Plasmodium falciparum Analysed by Direct Genome Sequencing from Peripheral Blood of Malaria Patients
Naturally acquired blood-stage infections of the malaria parasite Plasmodium falciparum typically harbour multiple haploid clones. The apparent number of clones observed in any single infection depends on the diversity of the polymorphic markers used for the analysis, and the relative abundance of r...
Autores principales: | Robinson, Timothy, Campino, Susana G., Auburn, Sarah, Assefa, Samuel A., Polley, Spencer D., Manske, Magnus, MacInnis, Bronwyn, Rockett, Kirk A., Maslen, Gareth L., Sanders, Mandy, Quail, Michael A., Chiodini, Peter L., Kwiatkowski, Dominic P., Clark, Taane G., Sutherland, Colin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154926/ https://www.ncbi.nlm.nih.gov/pubmed/21853089 http://dx.doi.org/10.1371/journal.pone.0023204 |
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