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Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty

BACKGROUND: Prolonged wound-discharge following total hip arthroplasty (THA) is associated with an increased risk of infection. However, the potential role of hypertension in prolonging the duration of wound healing in this population has not yet been investigated. The aim of the present study was t...

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Autores principales: Ahmed, Awad A., Mooar, Pekka A., Kleiner, Matthew, Torg, Joseph S., Miyamoto, Curtis T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154930/
https://www.ncbi.nlm.nih.gov/pubmed/21853091
http://dx.doi.org/10.1371/journal.pone.0023224
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author Ahmed, Awad A.
Mooar, Pekka A.
Kleiner, Matthew
Torg, Joseph S.
Miyamoto, Curtis T.
author_facet Ahmed, Awad A.
Mooar, Pekka A.
Kleiner, Matthew
Torg, Joseph S.
Miyamoto, Curtis T.
author_sort Ahmed, Awad A.
collection PubMed
description BACKGROUND: Prolonged wound-discharge following total hip arthroplasty (THA) is associated with an increased risk of infection. However, the potential role of hypertension in prolonging the duration of wound healing in this population has not yet been investigated. The aim of the present study was to compare healing in this population that has not yet been investigated. The aim of the present study was to compare hypertensive and normotensive THA patients in terms of the length of time required to achieve a dry wound and the length of stay in the hospital. METHODS: One hundred and twenty primary THA patients were evaluated. Pre-operative clinical history and physical examination revealed that 29 were hypertensive and 91 were normotensive. The two groups were statistically matched using optimal propensity score matching. The outcomes of interest were the number of days until a dry wound was observed and the duration of hospital stay. RESULTS: The average systolic blood pressures were 150.1 mmHg and 120.3 mmHg for the hypertensive and normotensive groups, respectively. The mean number of days until the wound was dry was 3.79 for the hypertensive group and 2.03 for the normotensive group. Hypertensive patients required more days for their wounds to dry than normotensive patients (odds ratio  = 1.65, p<0.05). No significant difference in the duration of hospital stay was found between the two groups. CONCLUSIONS: Hypertensive patients had a higher risk of prolonged wound discharge after THA than their normotensive counterparts. Patients with prolonged wound drainage are at greater risk for infection. Clinicians should pay particular attention to infection-prevention strategies in hypertensive THA patients.
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spelling pubmed-31549302011-08-18 Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty Ahmed, Awad A. Mooar, Pekka A. Kleiner, Matthew Torg, Joseph S. Miyamoto, Curtis T. PLoS One Research Article BACKGROUND: Prolonged wound-discharge following total hip arthroplasty (THA) is associated with an increased risk of infection. However, the potential role of hypertension in prolonging the duration of wound healing in this population has not yet been investigated. The aim of the present study was to compare healing in this population that has not yet been investigated. The aim of the present study was to compare hypertensive and normotensive THA patients in terms of the length of time required to achieve a dry wound and the length of stay in the hospital. METHODS: One hundred and twenty primary THA patients were evaluated. Pre-operative clinical history and physical examination revealed that 29 were hypertensive and 91 were normotensive. The two groups were statistically matched using optimal propensity score matching. The outcomes of interest were the number of days until a dry wound was observed and the duration of hospital stay. RESULTS: The average systolic blood pressures were 150.1 mmHg and 120.3 mmHg for the hypertensive and normotensive groups, respectively. The mean number of days until the wound was dry was 3.79 for the hypertensive group and 2.03 for the normotensive group. Hypertensive patients required more days for their wounds to dry than normotensive patients (odds ratio  = 1.65, p<0.05). No significant difference in the duration of hospital stay was found between the two groups. CONCLUSIONS: Hypertensive patients had a higher risk of prolonged wound discharge after THA than their normotensive counterparts. Patients with prolonged wound drainage are at greater risk for infection. Clinicians should pay particular attention to infection-prevention strategies in hypertensive THA patients. Public Library of Science 2011-08-11 /pmc/articles/PMC3154930/ /pubmed/21853091 http://dx.doi.org/10.1371/journal.pone.0023224 Text en Ahmed et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Ahmed, Awad A.
Mooar, Pekka A.
Kleiner, Matthew
Torg, Joseph S.
Miyamoto, Curtis T.
Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
title Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
title_full Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
title_fullStr Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
title_full_unstemmed Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
title_short Hypertensive Patients Show Delayed Wound Healing following Total Hip Arthroplasty
title_sort hypertensive patients show delayed wound healing following total hip arthroplasty
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154930/
https://www.ncbi.nlm.nih.gov/pubmed/21853091
http://dx.doi.org/10.1371/journal.pone.0023224
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