Structure and Dynamics of the Membrane-Bound Cytochrome P450 2C9

The microsomal, membrane-bound, human cytochrome P450 (CYP) 2C9 is a liver-specific monooxygenase essential for drug metabolism. CYPs require electron transfer from the membrane-bound CYP reductase (CPR) for catalysis. The structural details and functional relevance of the CYP-membrane interaction a...

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Detalles Bibliográficos
Autores principales: Cojocaru, Vlad, Balali-Mood, Kia, Sansom, Mark S. P., Wade, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154944/
https://www.ncbi.nlm.nih.gov/pubmed/21852944
http://dx.doi.org/10.1371/journal.pcbi.1002152

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