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A Two-Step Chemical Mechanism for Ribosome-Catalyzed Peptide Bond Formation
The chemical step of protein synthesis, peptide bond formation, is catalyzed by the large subunit of the ribosome. Crystal structures have demonstrated that the active site for peptide bond formation is composed entirely of RNA(1). Recent work has focused on how an RNA active site is able to catalyz...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3154986/ https://www.ncbi.nlm.nih.gov/pubmed/21765427 http://dx.doi.org/10.1038/nature10248 |