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Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress
Cancer cells produce galectin-1 as a tumor promoting protein. Thiodigalactoside (TDG) as a non-metabolised small drug, is shown to suppress tumor growth by inhibiting multiple cancer enhancing activities of galectin-1, including immune cell dysregulation, angiogenesis and protection against oxidativ...
Autores principales: | Ito, Koichi, Scott, Stacy A., Cutler, Samuel, Dong, Lan-Feng, Neuzil, Jiri, Blanchard, Helen, Ralph, Stephen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155035/ https://www.ncbi.nlm.nih.gov/pubmed/21523436 http://dx.doi.org/10.1007/s10456-011-9213-5 |
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