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Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na(+) transport in response to apical fluid volume expansion in human H441 airway epithelial cells
Using human H441 airway epithelial cells cultured at air–liquid interface (ALI), we have uniquely correlated the functional response to apical fluid volume expansion with the abundance and cleavage of endogenous α- and γENaC proteins in the apical membrane. Monolayers cultured at ALI rapidly elevate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer-Verlag
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155050/ https://www.ncbi.nlm.nih.gov/pubmed/21667229 http://dx.doi.org/10.1007/s00424-011-0982-x |