Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information

BACKGROUND: The monocarboxylate transporter 8 (MCT8) is a member of the major facilitator superfamily (MFS) and transports specificly iodothyronines. MCT8 mutations are the underlying cause of a syndrome of severe X-linked psychomotor retardation known as the Allan-Herndon-Dudley syndrome. This synd...

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Detalles Bibliográficos
Autores principales: Kleinau, Gunnar, Schweizer, Ulrich, Kinne, Anita, Köhrle, Josef, Grüters, Annette, Krude, Heiko, Biebermann, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155110/
https://www.ncbi.nlm.nih.gov/pubmed/21835051
http://dx.doi.org/10.1186/1756-6614-4-S1-S4

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