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Alloantigen-based AIDS vaccine: revisiting a "rightfully" discarded promising strategy

This report revisits the accidental discovery that protection against simian immunodeficiency virus (SIV) infection in the early successful experimental AIDS vaccine studies in Rhesus macaques was due to antibodies directed against human leukocyte antigens (HLAs). The inactivated virus vaccine appro...

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Detalles Bibliográficos
Autores principales: Shearer, Gene M., Boasso, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155155/
https://www.ncbi.nlm.nih.gov/pubmed/21876718
http://dx.doi.org/10.3410/M3-12