Cargando…
Molecular Interaction of TPPP with PrP Antagonized the CytoPrP-Induced Disruption of Microtubule Structures and Cytotoxicity
BACKGROUND: Tubulin polymerization promoting protein/p25 (TPPP/p25), known as a microtubule-associated protein (MAP), is a brain-specific unstructured protein with a physiological function of stabilizing cellular microtubular ultrastructures. Whether TPPP involves in the normal functions of PrP or t...
Autores principales: | Zhou, Rui-Min, Jing, Yuan-Yuan, Guo, Yan, Gao, Chen, Zhang, Bao-Yun, Chen, Cao, Shi, Qi, Tian, Chan, Wang, Zhao-Yun, Gong, Han-Shi, Han, Jun, Xu, Bian-Li, Dong, Xiao-Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155546/ https://www.ncbi.nlm.nih.gov/pubmed/21857997 http://dx.doi.org/10.1371/journal.pone.0023079 |
Ejemplares similares
-
Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
por: Sakudo, Akikazu, et al.
Publicado: (2015) -
Exploration of the Main Sites for the Transformation of Normal Prion Protein (PrP(C)) into Pathogenic Prion Protein (PrP(sc))
por: Liu, Xi-Lin, et al.
Publicado: (2017) -
The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018) -
PrP Expression, PrP(Sc) Accumulation and Innervation of Splenic Compartments in Sheep Experimentally Infected with Scrapie
por: Sørby, Randi, et al.
Publicado: (2009) -
Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)
por: McCarthy, James M., et al.
Publicado: (2013)