Onset of Quiescence Following p53 Mediated Down-Regulation of H2AX in Normal Cells

Normal cells, both in vivo and in vitro, become quiescent after serial cell proliferation. During this process, cells can develop immortality with genomic instability, although the mechanisms by which this is regulated are unclear. Here, we show that a growth-arrested cellular status is produced by...

Descripción completa

Detalles Bibliográficos
Autores principales: Atsumi, Yuko, Fujimori, Hiroaki, Fukuda, Hirokazu, Inase, Aki, Shinohe, Keitaro, Yoshioka, Yoshiko, Shikanai, Mima, Ichijima, Yosuke, Unno, Junya, Mizutani, Shuki, Tsuchiya, Naoto, Hippo, Yoshitaka, Nakagama, Hitoshi, Masutani, Mitsuko, Teraoka, Hirobumi, Yoshioka, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155552/
https://www.ncbi.nlm.nih.gov/pubmed/21858116
http://dx.doi.org/10.1371/journal.pone.0023432

Ejemplares similares

Ejemplares similares