Eukaryotic Cells Producing Ribosomes Deficient in Rpl1 Are Hypersensitive to Defects in the Ubiquitin-Proteasome System

It has recently become clear that the misassembly of ribosomes in eukaryotic cells can have deleterious effects that go far beyond a simple shortage of ribosomes. In this work we find that cells deficient in ribosomal protein L1 (Rpl1; Rpl10a in mammals) produce ribosomes lacking Rpl1 that are expor...

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Detalles Bibliográficos
Autores principales: McIntosh, Kerri B., Bhattacharya, Arpita, Willis, Ian M., Warner, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155557/
https://www.ncbi.nlm.nih.gov/pubmed/21858174
http://dx.doi.org/10.1371/journal.pone.0023579

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