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Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease
Sex-differences in human liver gene expression were characterized on a genome-wide scale using a large liver sample collection, allowing for detection of small expression differences with high statistical power. 1,249 sex-biased genes were identified, 70% showing higher expression in females. Chromo...
Autores principales: | Zhang, Yijing, Klein, Kathrin, Sugathan, Aarathi, Nassery, Najlla, Dombkowski, Alan, Zanger, Ulrich M., Waxman, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155567/ https://www.ncbi.nlm.nih.gov/pubmed/21858147 http://dx.doi.org/10.1371/journal.pone.0023506 |
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