Telomere shortening and loss of self-renewal in dyskeratosis congenita iPS cells

The differentiation of patient-derived induced pluripotent stem cells (iPSCs) to committed fates such as neurons, muscle and liver is a powerful approach for understanding key parameters of human development and disease(1–6). Whether undifferentiated iPSCs themselves can be used to probe disease mec...

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Detalles Bibliográficos
Autores principales: Batista, Luis F.Z., Pech, Matthew F., Zhong, Franklin L., Nguyen, Ha Nam, Xie, Kathleen T., Zaug, Arthur J., Crary, Sharon M., Choi, Jinkuk, Sebastiano, Vittorio, Cherry, Athena, Giri, Neelam, Wernig, Marius, Alter, Blanche P., Cech, Thomas R., Savage, Sharon A., Reijo Pera, Renee A., Artandi, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155806/
https://www.ncbi.nlm.nih.gov/pubmed/21602826
http://dx.doi.org/10.1038/nature10084

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