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Inactivation of the von Hippel-Lindau tumour suppressor gene induces Neuromedin U expression in renal cancer cells
BACKGROUND: 209 000 new cases of renal carcinoma are diagnosed each year worldwide and new therapeutic targets are urgently required. The great majority of clear cell renal cancer involves inactivation of VHL, which acts as a gatekeeper tumour suppressor gene in renal epithelial cells. However how V...
Autores principales: | Harten, Sarah K, Esteban, Miguel A, Shukla, Deepa, Ashcroft, Margaret, Maxwell, Patrick H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155908/ https://www.ncbi.nlm.nih.gov/pubmed/21791076 http://dx.doi.org/10.1186/1476-4598-10-89 |
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