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Protein-Selective Capture to Analyze Electrophile Adduction of Hsp90 by 4-Hydroxynonenal

[Image: see text] The analysis of protein modification by electrophiles is a challenging problem. Most reported protein–electrophile adducts have been characterized from in vitro reactions or through affinity capture of the adduct moiety, which enables global analyses but is poorly suited to targete...

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Detalles Bibliográficos
Autores principales: Connor, Rebecca E., Marnett, Lawrence J., Liebler, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155980/
https://www.ncbi.nlm.nih.gov/pubmed/21749116
http://dx.doi.org/10.1021/tx200157t