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Activation of Aryl Hydrocarbon Receptor (AhR) Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 Expression and Amelioration of Experimental Colitis
BACKGROUND: Aryl hydrocarbon receptor (AhR), a transcription factor of the bHLH/PAS family, is well characterized to regulate the biochemical and toxic effects of environmental chemicals. More recently, AhR activation has been shown to regulate the differentiation of Foxp3(+) Tregs as well as Th17 c...
Autores principales: | Singh, Narendra P., Singh, Udai P., Singh, Balwan, Price, Robert L., Nagarkatti, Mitzi, Nagarkatti, Prakash S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156147/ https://www.ncbi.nlm.nih.gov/pubmed/21858153 http://dx.doi.org/10.1371/journal.pone.0023522 |
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