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Soluble Beta-Amyloid Precursor Protein Is Related to Disease Progression in Amyotrophic Lateral Sclerosis
BACKGROUND: Biomarkers of disease progression in amyotrophic lateral sclerosis (ALS) could support the identification of beneficial drugs in clinical trials. We aimed to test whether soluble fragments of beta-amyloid precursor protein (sAPPα and sAPPß) correlated with clinical subtypes of ALS and we...
Autores principales: | Steinacker, Petra, Fang, Lubin, Kuhle, Jens, Petzold, Axel, Tumani, Hayrettin, Ludolph, Albert C., Otto, Markus, Brettschneider, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156148/ https://www.ncbi.nlm.nih.gov/pubmed/21858182 http://dx.doi.org/10.1371/journal.pone.0023600 |
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