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Opposing Effects of the Angiopoietins on the Thrombin-Induced Permeability of Human Pulmonary Microvascular Endothelial Cells

BACKGROUND: Angiopoietin-2 (Ang-2) is associated with lung injury in ALI/ARDS. As endothelial activation by thrombin plays a role in the permeability of acute lung injury and Ang-2 may modulate the kinetics of thrombin-induced permeability by impairing the organization of vascular endothelial (VE-)c...

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Detalles Bibliográficos
Autores principales:	van der Heijden, Melanie, van Nieuw Amerongen, Geerten P., van Bezu, Jan, Paul, Marinus A., Groeneveld, A. B. Johan, van Hinsbergh, Victor W. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156229/ https://www.ncbi.nlm.nih.gov/pubmed/21858121 http://dx.doi.org/10.1371/journal.pone.0023448

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