Diagnosing Autism Spectrum Disorders in Adults: the Use of Autism Diagnostic Observation Schedule (ADOS) Module 4

Autism Diagnostic Observation Schedule (ADOS) module 4 was investigated in an independent sample of high-functioning adult males with an autism spectrum disorder (ASD) compared to three specific diagnostic groups: schizophrenia, psychopathy, and typical development. ADOS module 4 proves to be a reli...

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Detalles Bibliográficos
Autores principales: Bastiaansen, Jojanneke A., Meffert, Harma, Hein, Simone, Huizinga, Petra, Ketelaars, Cees, Pijnenborg, Marieke, Bartels, Arnold, Minderaa, Ruud, Keysers, Christian, de Bildt, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156304/
https://www.ncbi.nlm.nih.gov/pubmed/21153873
http://dx.doi.org/10.1007/s10803-010-1157-x
Descripción
Sumario:Autism Diagnostic Observation Schedule (ADOS) module 4 was investigated in an independent sample of high-functioning adult males with an autism spectrum disorder (ASD) compared to three specific diagnostic groups: schizophrenia, psychopathy, and typical development. ADOS module 4 proves to be a reliable instrument with good predictive value. It can adequately discriminate ASD from psychopathy and typical development, but is less specific with respect to schizophrenia due to behavioral overlap between autistic and negative symptoms. However, these groups differ on some core items and explorative analyses indicate that a revision of the algorithm in line with Gotham et al. (J Autism Dev Disord 37: 613–627, 2007) could be beneficial for discriminating ASD from schizophrenia.

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