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ABT-737 and/or folate reverse the PDGF-induced alterations in the mitochondrial apoptotic pathway in low-grade glioma patients

Elevated activation of the platelet-derived growth factor (PDGF) pathway, apoptosis evasion phenotype, and global DNA hypomethylation are hallmarks frequently observed in cancers, such as in low-grade glioma (LGG). However, the orchestration of these malignant functions is not fully elucidated in LG...

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Detalles Bibliográficos
Autores principales:	Debien, Emilie, Hervouet, Eric, Gautier, Fabien, Juin, Philippe, Vallette, Francois M., Cartron, Pierre-Francois
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156333/ https://www.ncbi.nlm.nih.gov/pubmed/21949549 http://dx.doi.org/10.1007/s13148-011-0035-5

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