Establishment of clonal myogenic cell lines from severely affected dystrophic muscles - CDK4 maintains the myogenic population

BACKGROUND: A hallmark of muscular dystrophies is the replacement of muscle by connective tissue. Muscle biopsies from patients severely affected with facioscapulohumeral muscular dystrophy (FSHD) may contain few myogenic cells. Because the chromosomal contraction at 4q35 linked to FSHD is thought t...

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Detalles Bibliográficos
Autores principales: Stadler, Guido, Chen, Jennifer CJ, Wagner, Kathryn, Robin, Jerome D, Shay, Jerry W, Emerson Jr, Charles P, Wright, Woodring E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156635/
https://www.ncbi.nlm.nih.gov/pubmed/21798090
http://dx.doi.org/10.1186/2044-5040-1-12

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