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Challenges to oligonucleotides-based therapeutics for Duchenne muscular dystrophy
Antisense oligonucleotides are short nucleic acids designed to bind to specific messenger RNAs in order to modulate splicing patterns or inhibit protein translation. As such, they represent promising therapeutic tools for many disorders and have been actively developed for more than 20 years as a fo...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156649/ https://www.ncbi.nlm.nih.gov/pubmed/21798085 http://dx.doi.org/10.1186/2044-5040-1-8 |