IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis is a devastating as yet untreatable disease. We demonstrated recently the predominant role of the NLRP3 inflammasome activation and IL-1β expression in the establishment of pulmonary inflammation and fibrosis in mice. METHODS: The contribution of IL-23 or IL...

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Detalles Bibliográficos
Autores principales: Gasse, Paméla, Riteau, Nicolas, Vacher, Rachel, Michel, Marie-Laure, Fautrel, Alain, di Padova, Franco, Fick, Lizette, Charron, Sabine, Lagente, Vincent, Eberl, Gérard, Le Bert, Marc, Quesniaux, Valérie F. J., Huaux, François, Leite-de-Moraes, Maria, Ryffel, Bernhard, Couillin, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156735/
https://www.ncbi.nlm.nih.gov/pubmed/21858022
http://dx.doi.org/10.1371/journal.pone.0023185

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