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Longevity in Mice Is Promoted by Probiotic-Induced Suppression of Colonic Senescence Dependent on Upregulation of Gut Bacterial Polyamine Production
BACKGROUND: Chronic low-grade inflammation is recognized as an important factor contributing to senescence and age-related diseases. In mammals, levels of polyamines (PAs) decrease during the ageing process; PAs are known to decrease systemic inflammation by inhibiting inflammatory cytokine synthesi...
Autores principales: | Matsumoto, Mitsuharu, Kurihara, Shin, Kibe, Ryoko, Ashida, Hisashi, Benno, Yoshimi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156754/ https://www.ncbi.nlm.nih.gov/pubmed/21858192 http://dx.doi.org/10.1371/journal.pone.0023652 |
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