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Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report

INTRODUCTION: Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-inv...

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Autores principales: Braun, Stephan, Reimer, Daniel, Strobl, Isolde, Wieland, Ulrike, Wiesbauer, Petra, Müller-Holzner, Elisabeth, Fessler, Siegfried, Scherer, Arthur, Marth, Christian, Zeimet, Alain G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156764/
https://www.ncbi.nlm.nih.gov/pubmed/21767367
http://dx.doi.org/10.1186/1752-1947-5-316
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author Braun, Stephan
Reimer, Daniel
Strobl, Isolde
Wieland, Ulrike
Wiesbauer, Petra
Müller-Holzner, Elisabeth
Fessler, Siegfried
Scherer, Arthur
Marth, Christian
Zeimet, Alain G
author_facet Braun, Stephan
Reimer, Daniel
Strobl, Isolde
Wieland, Ulrike
Wiesbauer, Petra
Müller-Holzner, Elisabeth
Fessler, Siegfried
Scherer, Arthur
Marth, Christian
Zeimet, Alain G
author_sort Braun, Stephan
collection PubMed
description INTRODUCTION: Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-invasive and early-stage invasive lesions. CASE PRESENTATION: We present a well-documented case of a 29-year-old Caucasian woman who was found, through routine conventional cervical cytology screening, to have pathologic Papanicolaou (Pap) grade III D lesions (squamous cell abnormalities). She subsequently died as a result of human papillomavirus type 18-associated cervical cancer after she refused all recommended curative therapeutic procedures over a period of 13 years. CONCLUSION: This case clearly demonstrates a caveat against the promotion and use of complementary alternative medicine as pseudo-immunologic approaches outside evidence-based medicine paths. It also demonstrates the impact of the individualized demands in diagnosis, treatment and palliative care of patients with advanced cancer express their will to refuse evidence-based treatment recommendations.
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spelling pubmed-31567642011-08-17 Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report Braun, Stephan Reimer, Daniel Strobl, Isolde Wieland, Ulrike Wiesbauer, Petra Müller-Holzner, Elisabeth Fessler, Siegfried Scherer, Arthur Marth, Christian Zeimet, Alain G J Med Case Reports Case Report INTRODUCTION: Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-invasive and early-stage invasive lesions. CASE PRESENTATION: We present a well-documented case of a 29-year-old Caucasian woman who was found, through routine conventional cervical cytology screening, to have pathologic Papanicolaou (Pap) grade III D lesions (squamous cell abnormalities). She subsequently died as a result of human papillomavirus type 18-associated cervical cancer after she refused all recommended curative therapeutic procedures over a period of 13 years. CONCLUSION: This case clearly demonstrates a caveat against the promotion and use of complementary alternative medicine as pseudo-immunologic approaches outside evidence-based medicine paths. It also demonstrates the impact of the individualized demands in diagnosis, treatment and palliative care of patients with advanced cancer express their will to refuse evidence-based treatment recommendations. BioMed Central 2011-07-18 /pmc/articles/PMC3156764/ /pubmed/21767367 http://dx.doi.org/10.1186/1752-1947-5-316 Text en Copyright ©2011 Braun et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Braun, Stephan
Reimer, Daniel
Strobl, Isolde
Wieland, Ulrike
Wiesbauer, Petra
Müller-Holzner, Elisabeth
Fessler, Siegfried
Scherer, Arthur
Marth, Christian
Zeimet, Alain G
Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
title Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
title_full Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
title_fullStr Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
title_full_unstemmed Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
title_short Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
title_sort fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156764/
https://www.ncbi.nlm.nih.gov/pubmed/21767367
http://dx.doi.org/10.1186/1752-1947-5-316
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