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Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report
INTRODUCTION: Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-inv...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156764/ https://www.ncbi.nlm.nih.gov/pubmed/21767367 http://dx.doi.org/10.1186/1752-1947-5-316 |
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author | Braun, Stephan Reimer, Daniel Strobl, Isolde Wieland, Ulrike Wiesbauer, Petra Müller-Holzner, Elisabeth Fessler, Siegfried Scherer, Arthur Marth, Christian Zeimet, Alain G |
author_facet | Braun, Stephan Reimer, Daniel Strobl, Isolde Wieland, Ulrike Wiesbauer, Petra Müller-Holzner, Elisabeth Fessler, Siegfried Scherer, Arthur Marth, Christian Zeimet, Alain G |
author_sort | Braun, Stephan |
collection | PubMed |
description | INTRODUCTION: Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-invasive and early-stage invasive lesions. CASE PRESENTATION: We present a well-documented case of a 29-year-old Caucasian woman who was found, through routine conventional cervical cytology screening, to have pathologic Papanicolaou (Pap) grade III D lesions (squamous cell abnormalities). She subsequently died as a result of human papillomavirus type 18-associated cervical cancer after she refused all recommended curative therapeutic procedures over a period of 13 years. CONCLUSION: This case clearly demonstrates a caveat against the promotion and use of complementary alternative medicine as pseudo-immunologic approaches outside evidence-based medicine paths. It also demonstrates the impact of the individualized demands in diagnosis, treatment and palliative care of patients with advanced cancer express their will to refuse evidence-based treatment recommendations. |
format | Online Article Text |
id | pubmed-3156764 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-31567642011-08-17 Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report Braun, Stephan Reimer, Daniel Strobl, Isolde Wieland, Ulrike Wiesbauer, Petra Müller-Holzner, Elisabeth Fessler, Siegfried Scherer, Arthur Marth, Christian Zeimet, Alain G J Med Case Reports Case Report INTRODUCTION: Well-documented cases of untreated cervical intra-epithelial dysplasia resulting in fatal progression of invasive cervical cancer are scarce because of a long pre-invasive state, the availability of cervical cytology screening programs, and the efficacy of the treatment of both pre-invasive and early-stage invasive lesions. CASE PRESENTATION: We present a well-documented case of a 29-year-old Caucasian woman who was found, through routine conventional cervical cytology screening, to have pathologic Papanicolaou (Pap) grade III D lesions (squamous cell abnormalities). She subsequently died as a result of human papillomavirus type 18-associated cervical cancer after she refused all recommended curative therapeutic procedures over a period of 13 years. CONCLUSION: This case clearly demonstrates a caveat against the promotion and use of complementary alternative medicine as pseudo-immunologic approaches outside evidence-based medicine paths. It also demonstrates the impact of the individualized demands in diagnosis, treatment and palliative care of patients with advanced cancer express their will to refuse evidence-based treatment recommendations. BioMed Central 2011-07-18 /pmc/articles/PMC3156764/ /pubmed/21767367 http://dx.doi.org/10.1186/1752-1947-5-316 Text en Copyright ©2011 Braun et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Braun, Stephan Reimer, Daniel Strobl, Isolde Wieland, Ulrike Wiesbauer, Petra Müller-Holzner, Elisabeth Fessler, Siegfried Scherer, Arthur Marth, Christian Zeimet, Alain G Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
title | Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
title_full | Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
title_fullStr | Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
title_full_unstemmed | Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
title_short | Fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
title_sort | fatal invasive cervical cancer secondary to untreated cervical dysplasia: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156764/ https://www.ncbi.nlm.nih.gov/pubmed/21767367 http://dx.doi.org/10.1186/1752-1947-5-316 |
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