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Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1

The mechanisms underlying the Hepatitis C virus (HCV) resistance to interferon alpha (IFN-α) are not fully understood. We used IFN-α resistant HCV replicon cell lines and an infectious HCV cell culture system to elucidate the mechanisms of IFN-α resistance in cell culture. The IFN-α resistance mecha...

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Detalles Bibliográficos
Autores principales:	Datta, Sibnarayan, Hazari, Sidhartha, Chandra, Partha K, Samara¹, Maria, Poat, Bret, Gunduz, Feyza, Wimley, William C, Hauser, Hansjorg, Koster, Mario, Lamaze, Christophe, Balart, Luis A, Garry, Robert F, Dash, Srikanta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156775/ https://www.ncbi.nlm.nih.gov/pubmed/21756311 http://dx.doi.org/10.1186/1743-422X-8-351

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