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Intravitreal homocysteine-thiolactone injection leads to the degeneration of multiple retinal cells, including photoreceptors
PURPOSE: Hyperhomocysteinemia is known to cause degeneration of retinal ganglion cells, but its influence on photoreceptors remains largely unknown. In particular, the role of homocysteine-thiolactone (Hcy-T)—the physiologic metabolite of homocysteine that has been proven to be more cytotoxic than h...
Autores principales: | Chang, Han-Hsin, Lin, David Pei-Cheng, Chen, Ying-Shan, Liu, Hsiang-Jui, Lin, Wei, Tsao, Zih-Jay, Teng, Mei-Ching, Chen, Bo-Yie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156793/ https://www.ncbi.nlm.nih.gov/pubmed/21850169 |
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