Cargando…

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

BACKGROUND: Although the prognostic value of the ATP-binding cassette, subfamily C (ABCC) transporters in childhood neuroblastoma is usually attributed to their role in cytotoxic drug efflux, certain observations have suggested that these multidrug transporters might contribute to the malignant phen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Henderson, Michelle J., Haber, Michelle, Porro, Antonio, Munoz, Marcia A., Iraci, Nunzio, Xue, Chengyuan, Murray, Jayne, Flemming, Claudia L., Smith, Janice, Fletcher, Jamie I., Gherardi, Samuele, Kwek, Chin-Kiat, Russell, Amanda J., Valli, Emanuele, London, Wendy B., Buxton, Allen B., Ashton, Lesley J., Sartorelli, Alan C., Cohn, Susan L., Schwab, Manfred, Marshall, Glenn M., Perini, Giovanni, Norris, Murray D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156802/ https://www.ncbi.nlm.nih.gov/pubmed/21799180 http://dx.doi.org/10.1093/jnci/djr256

Ejemplares similares

ABCC4/MRP4: a MYCN-regulated transporter and potential therapeutic target in neuroblastoma
por: Huynh, Tony, et al.
Publicado: (2012)

MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma
por: Lau, Diana T., et al.
Publicado: (2015)

MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4
por: Xue, Chengyuan, et al.
Publicado: (2016)

Characterization of Zebrafish Abcc4 as an Efflux Transporter of Organochlorine Pesticides
por: Lu, Xing, et al.
Publicado: (2014)

Implications of ABCC4–Mediated cAMP Efflux for CRC Migration
por: Kryczka, Jakub, et al.
Publicado: (2020)

Comparative Molecular Docking Studies with ABCC1 and Aquaporin 9 in the Arsenite Complex Efflux
por: Poojan, Shiv, et al.
Publicado: (2014)

Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead
por: Lu, Xing, et al.
Publicado: (2021)

Differential Regulation of Glucosylceramide Synthesis and Efflux by Golgi and Plasma Membrane Bound ABCC10
por: Iqbal, Jahangir, et al.
Publicado: (2023)

Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer
por: Chen, Jihui, et al.
Publicado: (2021)

Recent advances regarding the role of ABC subfamily C member 10 (ABCC10) in the efflux of antitumor drugs
por: Kathawala, Rishil J., et al.
Publicado: (2014)

SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability
por: Marshall, Glenn M., et al.
Publicado: (2011)

MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin
por: Gherardi, Samuele, et al.
Publicado: (2013)

Correction to: Human drug efflux transporter ABCC5 confers acquired resistance to pemetrexed in breast cancer
por: Chen, Jihui, et al.
Publicado: (2021)

Tandutinib (MLN518) reverses multidrug resistance by inhibiting the efflux activity of the multidrug resistance protein 7 (ABCC10)
por: DENG, WEN, et al.
Publicado: (2013)

Imatinib and Nilotinib Reverse Multidrug Resistance in Cancer Cells by Inhibiting the Efflux Activity of the MRP7 (ABCC10)
por: Shen, Tong, et al.
Publicado: (2009)

Synthesis and Biological Evaluation of Pentacyclic Strychnos Alkaloids as Selective Modulators of the ABCC10 (MRP7) Efflux Pump
por: Teijaro, Christiana N., et al.
Publicado: (2014)

Correction: Imatinib and Nilotinib Reverse Multidrug Resistance in Cancer Cells by Inhibiting the Efflux Activity of the MRP7 (ABCC10)
por: Shen, Tong, et al.
Publicado: (2009)

Increased ABCC4 Expression Induced by ERRα Leads to Docetaxel Resistance via Efflux of Docetaxel in Prostate Cancer
por: Huang, Houbao, et al.
Publicado: (2020)

Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines
por: Low, Floren G., et al.
Publicado: (2020)

BBA, a Synthetic Derivative of 23-hydroxybutulinic Acid, Reverses Multidrug Resistance by Inhibiting the Efflux Activity of MRP7 (ABCC10)
por: Chen, Jun-Jiang, et al.
Publicado: (2013)

Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer
por: Gao, Bo, et al.
Publicado: (2014)

Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine
por: Adema, Auke D, et al.
Publicado: (2014)

ABCC9 Is Downregulated and Prone to Microsatellite Instability on ABCC9tetra in Canine Breast Cancer
por: Hao, Pan, et al.
Publicado: (2022)

Characterisation of the roles of ABCB1, ABCC1, ABCC2 and ABCG2 in the transport and pharmacokinetics of actinomycin D in vitro and in vivo
por: Hill, Christopher R., et al.
Publicado: (2013)

Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux
por: Bormio Nunes, Julia H., et al.
Publicado: (2020)

Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7
por: Chen, Haojie, et al.
Publicado: (2022)

Clinicopathological Impact of ABCC1/MRP1 and ABCC4/MRP4 in Epithelial Ovarian Carcinoma
por: Bagnoli, Marina, et al.
Publicado: (2013)

Three novel ABCC5 splice variants in human retina and their role as regulators of ABCC5 gene expression
por: Stojic, Jelena, et al.
Publicado: (2007)

Nanobodies targeting ABCC3 for immunotargeted applications in glioblastoma
por: Ruiz-López, Eduardo, et al.
Publicado: (2022)

ABCC6 and Pseudoxanthoma Elasticum: The Face of a Rare Disease from Genetics to Advocacy
por: Moitra, Karobi, et al.
Publicado: (2017)

An ABCC8 Nonsense Mutation Causing Neonatal Diabetes Through Altered Transcript Expression
por: Flanagan, Sarah E., et al.
Publicado: (2017)

ABCC6 Mutation in Patients with Angioid Streaks
por: Mizutani, Yoshihiro, et al.
Publicado: (2006)

Is ABCC6 a genuine mitochondrial protein?
por: Ferré, Marc, et al.
Publicado: (2013)

ABCC6 deficiency promotes dyslipidemia and atherosclerosis
por: Brampton, Christopher, et al.
Publicado: (2021)

Copy number variation in the ATP-binding cassette transporter ABCC6 gene and ABCC6 pseudogenes in patients with pseudoxanthoma elasticum
por: Kringen, Marianne K, et al.
Publicado: (2015)

ABCC9-related Intellectual disability Myopathy Syndrome is a K(ATP) channelopathy with loss-of-function mutations in ABCC9
por: Smeland, Marie F., et al.
Publicado: (2019)

Founder genetic variants of ABCC4 and ABCC11 in the Japanese population are not associated with the development of subacute myelo‐optico‐neuropathy (SMON)
por: Matsumoto, Hideki, et al.
Publicado: (2021)

Plasma Level of Pyrophosphate Is Low in Pseudoxanthoma Elasticum Owing to Mutations in the ABCC6 Gene, but It Does Not Correlate with ABCC6 Genotype
por: Kozák, Eszter, et al.
Publicado: (2023)

Bixin and Fuxoxanthin Alone and in Combination with Cisplatin Regulate ABCC1 and ABCC2 Transcription in A549 Lung Cancer Cells
por: Chandra, Ferdy, et al.
Publicado: (2023)

Role of RND Efflux Pumps in Drug Resistance of Cystic Fibrosis Pathogens
por: Scoffone, Viola Camilla, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ok1kotog7auok9jgvrl04ekdog