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Extracellular Calcium Reduction Strongly Increases the Lytic Capacity of Pneumolysin From Streptococcus Pneumoniae in Brain Tissue

Background. Streptococcus pneumoniae causes serious diseases such as pneumonia and meningitis. Its major pathogenic factor is the cholesterol-dependent cytolysin pneumolysin, which produces lytic pores at high concentrations. At low concentrations, it has other effects, including induction of apopto...

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Detalles Bibliográficos
Autores principales:	Wippel, Carolin, Förtsch, Christina, Hupp, Sabrina, Maier, Elke, Benz, Roland, Ma, Jiangtao, Mitchell, Timothy J., Iliev, Asparouh I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Major Articles and Brief Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156923/ https://www.ncbi.nlm.nih.gov/pubmed/21849290 http://dx.doi.org/10.1093/infdis/jir434

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