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In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel

BACKGROUND: The purpose of this study was to develop folate-poly (PEG-cyanoacrylate-co-cholesteryl cyanoacrylate) (FA-PEG-PCHL)-modified freeze-dried liposomes for targeted chemotherapy using docetaxel as a model drug. METHODS: FA-PEG-PCHL was synthesized and its cytotoxicity was evaluated by CCK-8...

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Detalles Bibliográficos
Autores principales:	Li, Xiang, Tian, Xin, Zhang, Jing, Zhao, Xu, Chen, Xiaohui, Jiang, Youhong, Wang, Dongkai, Pan, Weisan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2011
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157330/ https://www.ncbi.nlm.nih.gov/pubmed/21852896 http://dx.doi.org/10.2147/IJN.S21445

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