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A Booster Vaccine Expressing a Latency-Associated Antigen Augments BCG Induced Immunity and Confers Enhanced Protection against Tuberculosis

BACKGROUND: In spite of a consistent protection against tuberculosis (TB) in children, Mycobacterium bovis Bacille Calmette-Guerin (BCG) fails to provide adequate protection against the disease in adults as well as against reactivation of latent infections or exogenous reinfections. It has been spec...

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Detalles Bibliográficos
Autores principales:	Dey, Bappaditya, Jain, Ruchi, Gupta, Umesh D., Katoch, V. M., Ramanathan, V. D., Tyagi, Anil K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157374/ https://www.ncbi.nlm.nih.gov/pubmed/21858087 http://dx.doi.org/10.1371/journal.pone.0023360

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