Molecular Basis for the Recognition of Adenomatous Polyposis Coli by the Discs Large 1 Protein

The human Discs Large 1 (DLG1) protein uses two of its three PDZ domains to interact with the C-terminal peptide of the Adenomatous Polyposis Coli (APC) tumor suppressor protein. The DLG1/APC complex inhibits the cell cycle progression from the G0/G1 to the S phase, regulates epithelial cell migrati...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenyi, Li, Hua, Chen, Leyi, Lu, Xingyu, Zhang, Jian, Xu, Ping, Lin, Kui, Wu, Geng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157396/
https://www.ncbi.nlm.nih.gov/pubmed/21858148
http://dx.doi.org/10.1371/journal.pone.0023507

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