Alteration of Forkhead Box O (Foxo4) Acetylation Mediates Apoptosis of Podocytes in Diabetes Mellitus

The number of kidney podocytes is reduced in diabetic nephropathy. Advanced glycation end products (AGEs) accumulate in patients with diabetes and promote the apoptosis of podocyte by activating the forkhead box O4 (Foxo4) transcription factor to increase the expression of a pro-apoptosis gene, Bcl2...

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Detalles Bibliográficos
Autores principales: Chuang, Peter Y., Dai, Yan, Liu, Ruijie, He, Helen, Kretzler, Matthias, Jim, Belinda, Cohen, Clemens D., He, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157434/
https://www.ncbi.nlm.nih.gov/pubmed/21858169
http://dx.doi.org/10.1371/journal.pone.0023566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157434/
https://www.ncbi.nlm.nih.gov/pubmed/21858169
http://dx.doi.org/10.1371/journal.pone.0023566

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