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Urokinase Plasminogen Activator Inhibits HIV Virion Release from Macrophage-Differentiated Chronically Infected Cells via Activation of RhoA and PKCε

BACKGROUND: HIV replication in mononuclear phagocytes is a multi-step process regulated by viral and cellular proteins with the peculiar feature of virion budding and accumulation in intra-cytoplasmic vesicles. Interaction of urokinase-type plasminogen activator (uPA) with its cell surface receptor...

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Detalles Bibliográficos
Autores principales:	Graziano, Francesca, Elia, Chiara, Laudanna, Carlo, Poli, Guido, Alfano, Massimo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157461/ https://www.ncbi.nlm.nih.gov/pubmed/21858203 http://dx.doi.org/10.1371/journal.pone.0023674

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