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Curcumin Induces EGFR Degradation in Lung Adenocarcinoma and Modulates p38 Activation in Intestine: The Versatile Adjuvant for Gefitinib Therapy

BACKGROUND: Non-small cell lung cancer (NSCLC) patients with L858R or exon 19 deletion mutations in epidermal growth factor receptor (EGFR) have good responses to the tyrosine kinase inhibitor (TKI), gefitinib. However, patients with wild-type EGFR and acquired mutation in EGFR T790M are resistant t...

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Detalles Bibliográficos
Autores principales:	Lee, Jen-Yi, Lee, Yee-Ming, Chang, Gee-Chen, Yu, Sung-Liang, Hsieh, Wan-Yu, Chen, Jeremy J. W., Chen, Huei-Wen, Yang, Pan-Chyr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157465/ https://www.ncbi.nlm.nih.gov/pubmed/21858220 http://dx.doi.org/10.1371/journal.pone.0023756

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