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Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study

BACKGROUND: Generalized anxiety disorder (GAD) is often presented with major depression (MD). GAD-MD can be a chronic and disabling condition, and patients suffering from this disorder often respond poorly to psychopharmacological treatment and experience side effects with medication. Therefore, the...

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Autores principales: Olivieri, Elisabetta Bourget, Vecchiato, Caterina, Ignaccolo, Nunziatina, Mannu, Piero, Castagna, Alessandro, Aravagli, Lucia, Fontani, Vania, Rinaldi, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157488/
https://www.ncbi.nlm.nih.gov/pubmed/21857785
http://dx.doi.org/10.2147/NDT.S23420
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author Olivieri, Elisabetta Bourget
Vecchiato, Caterina
Ignaccolo, Nunziatina
Mannu, Piero
Castagna, Alessandro
Aravagli, Lucia
Fontani, Vania
Rinaldi, Salvatore
author_facet Olivieri, Elisabetta Bourget
Vecchiato, Caterina
Ignaccolo, Nunziatina
Mannu, Piero
Castagna, Alessandro
Aravagli, Lucia
Fontani, Vania
Rinaldi, Salvatore
author_sort Olivieri, Elisabetta Bourget
collection PubMed
description BACKGROUND: Generalized anxiety disorder (GAD) is often presented with major depression (MD). GAD-MD can be a chronic and disabling condition, and patients suffering from this disorder often respond poorly to psychopharmacological treatment and experience side effects with medication. Therefore, there is a high demand for effective nonpharmacological therapy for GAD-MD patients. The current study explores the use of a radioelectric asymmetric conveyer (REAC) device in the treatment of GAD-MD. METHODS: Participants were 24 patients diagnosed with GAD-MD being treated at a public psychiatric center. All patients were dissatisfied with their current pharmacological treatment. Patients were evaluated using the 21-item Hamilton Depression (HAM-D) rating scale and the Symptom Check List-90-Revised (SCL-90R) before and after REAC brain stimulation treatment cycles. RESULTS: After REAC brain stimulation treatment, all patients experienced a significant reduction in anxiety and depression. These results were confirmed by physician examination, HAM-D scores, and SCL-90R total scores. CONCLUSION: These results indicate a role for REAC brain stimulation in the management of psychiatric conditions, specifically, GAD-MD comorbidity. REAC treatments are synergistic to drug therapy and appear to be helpful in reducing the side effects of medication. Future studies should evaluate the long-term effects of REAC treatment.
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spelling pubmed-31574882011-08-19 Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study Olivieri, Elisabetta Bourget Vecchiato, Caterina Ignaccolo, Nunziatina Mannu, Piero Castagna, Alessandro Aravagli, Lucia Fontani, Vania Rinaldi, Salvatore Neuropsychiatr Dis Treat Original Research BACKGROUND: Generalized anxiety disorder (GAD) is often presented with major depression (MD). GAD-MD can be a chronic and disabling condition, and patients suffering from this disorder often respond poorly to psychopharmacological treatment and experience side effects with medication. Therefore, there is a high demand for effective nonpharmacological therapy for GAD-MD patients. The current study explores the use of a radioelectric asymmetric conveyer (REAC) device in the treatment of GAD-MD. METHODS: Participants were 24 patients diagnosed with GAD-MD being treated at a public psychiatric center. All patients were dissatisfied with their current pharmacological treatment. Patients were evaluated using the 21-item Hamilton Depression (HAM-D) rating scale and the Symptom Check List-90-Revised (SCL-90R) before and after REAC brain stimulation treatment cycles. RESULTS: After REAC brain stimulation treatment, all patients experienced a significant reduction in anxiety and depression. These results were confirmed by physician examination, HAM-D scores, and SCL-90R total scores. CONCLUSION: These results indicate a role for REAC brain stimulation in the management of psychiatric conditions, specifically, GAD-MD comorbidity. REAC treatments are synergistic to drug therapy and appear to be helpful in reducing the side effects of medication. Future studies should evaluate the long-term effects of REAC treatment. Dove Medical Press 2011 2011-08-04 /pmc/articles/PMC3157488/ /pubmed/21857785 http://dx.doi.org/10.2147/NDT.S23420 Text en © 2011 Olivieri et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Olivieri, Elisabetta Bourget
Vecchiato, Caterina
Ignaccolo, Nunziatina
Mannu, Piero
Castagna, Alessandro
Aravagli, Lucia
Fontani, Vania
Rinaldi, Salvatore
Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
title Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
title_full Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
title_fullStr Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
title_full_unstemmed Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
title_short Radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
title_sort radioelectric brain stimulation in the treatment of generalized anxiety disorder with comorbid major depression in a psychiatric hospital: a pilot study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157488/
https://www.ncbi.nlm.nih.gov/pubmed/21857785
http://dx.doi.org/10.2147/NDT.S23420
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