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Markovian and Non-Markovian Protein Sequence Evolution: Aggregated Markov Process Models

Over the years, there have been claims that evolution proceeds according to systematically different processes over different timescales and that protein evolution behaves in a non-Markovian manner. On the other hand, Markov models are fundamental to many applications in evolutionary studies. Appare...

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Detalles Bibliográficos
Autores principales: Kosiol, Carolin, Goldman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157587/
https://www.ncbi.nlm.nih.gov/pubmed/21718704
http://dx.doi.org/10.1016/j.jmb.2011.06.005